Kurzfassung

The goal of the proposed analyses is to identify pre-operatively assessed stress-related demographic characteristics (i.e., marital status, low educational attainment, working for income) and psychological stress factors (i.e., poor quality of life, particularly anxiety/depression, high pain/discomfort, low self-rated health, smoking) as predictors of outcomes and adverse events in male and female adult continuous flow LVAD recipients of different age groups in the European Registry for...The goal of the proposed analyses is to identify pre-operatively assessed stress-related demographic characteristics (i.e., marital status, low educational attainment, working for income) and psychological stress factors (i.e., poor quality of life, particularly anxiety/depression, high pain/discomfort, low self-rated health, smoking) as predictors of outcomes and adverse events in male and female adult continuous flow LVAD recipients of different age groups in the European Registry for Patients with Mechanical Circulatory Support (EUROMACS).
Specifically, we aim to:
1) Examine sex differences in pre-operatively assessed stress-related demographic characteristics, EQ-5D data, self-rated health, smoking, and medical characteristics of continuous flow LVAD recipients of different age groups.
2) Identify stress-related factors as predictors of outcomes (i.e., alive with device in place, transplant, death, recovered) and adverse events in female and male continuous flow LVAD recipients, controlling for disease severity (e.g., INTERMACS levels) and other covariates.
3) Compare and discuss our findings from EUROMACS data with respective INTERMACS findings at an international expert workshop to be held in Berlin in 2019.
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