Nichtsteroidale Antiphlogistika, Arachidonsäure-Kaskade, Adhäsion
Laufzeit: ab 01.01.1978
Partner: Prof. Dr. Hartmann; Prof. Dr. S. Laufer; Prof. Dr. J. L. Wallace
Kurzfassung
Nichtsteroidale Antiphlogistika, Arachidonsäure-Kaskade, Biotransformation der Arachidonsäure, Mechanismen der Enzymprozesse, neue nichtsteroidale Rheumamittel, inhibitorische Potenz und Enzymselektivität, Reduktion der unerwünschten Effekte im Gastrointestinaltrakt, Adhäsions-Inhibitoren, Aufbau von Testsystemen.
Veröffentlichungen
- Dannhardt, G.; Kiefer, W.
- Coxibs and central processing of pain - an update
- Dannhardt, G.; Ulbrich, H.; Prech, P. et al.
- Development of a computerized in vitro assay for the investigation of antiadhesive compounds
- Kiefer, W.; Dannhardt, G.
- Novel Insights and Therapeutical Applications in the Field of Inhibitors of COX-2
- Banwell, M. G.; Bezos, A.; Chand, S. et al.
- Convergent synthesis and preliminary biological evaluations of the stilbenolignan (+)-aiphanol and various congeners
- Dannhardt, Gerd; Fiebich, Bernd L.; Schweppenhäuser, Johannes
- COX-1-COX-2 inhibitors based on the methanone moiety
- Dannhardt, G.; Kiefer, W.
- COX-2 inhibition and the control of pain
- Ulbrich, Holger; Fiebich, Bernd; Dannhardt, Gerd
- Cyclooxygenase-1-2 (COX-1-COX-2) and 5-lipoxygenase (5-LOX) inhibitors of the 6,7-diaryl-2,3-1H-dihydropyrrolizine type
- Danz, Henning; Stoyanova, Stefka; Thomet, Olivier A. et al.
- Inhibitory Activity of Tryptanthrin on Prostaglandin and Leukotriene Synthesis
- Dannhardt, Gerd; Kiefer, Werner
- Cyclooxygenase inhibitors - current status and future prospects
- Jacobs, Christoph; Frotscher, Martin; Dannhardt, Gerd et al.
- Articles - 1-Imidazolyl(alkyl)-Substituted Di- and Tetrahydroquinolines and Analogues: Syntheses and Evaluation of Dual Inhibitors of Thromboxane A2 Synthase and Aromatase
- Dannenberg, Gerd; Hahn, Linda; Dannhardt, Gerd
- COX-2-Inhibitoren: Aktueller Stand und Ausblick
- Dannhardt, G.; Kiefer, W.; Krämer, G. et al.
- Original articles - The pyrrole moiety as a template for COX-1-COX-2-inhibitors
- Dannhardt, G.; Laufer, S.
- Structural Approaches to Explain the Selectivity of COX-2 Inhibitors: Is There a Common Pharmacophore?
- Dannhardt, Gerd; Kiefer, Werner; Nowe, Ulrike
- Non-steroidal Anti-inflammatory Agents, Part 19: E-2-Pyrrolizin-5-yl Acrylic Acids as Potent Dual or Selective Inhibitors of Bovine Cyclooxygenase and 5-Lipoxygenase
- Laufer, Stefan A.; Augustin, Jan; Dannhardt, Gerd et al.
- (6,7-Diaryldihydropyrrolizin-5-yl)acetic Acids, a Novel Class of Potent Dual Inhibitors of Both Cyclooxygenase and 5-Lipoxygenase
