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SFB 1080/2 C05 Homeostatic stabilization of neural function in a dynamic network

Laufzeit: 01.01.2017 - 31.12.2020

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Kurzfassung


Dynamic remodeling of connectivity is a fundamental feature of neocortical circuits. The aim of this project is unravel homeostatic mechanisms that ensure functional stability of neuronal ensembles forming auditory representations in a dynamic cortical architecture. To that goal, we combine in vivo two-photon imaging approaches in mice with theoretical modelling with our collaboration partner Prof. Yonatan Loewenstein at the Hebrew University in Jerusalem, to elucidate the link between...Dynamic remodeling of connectivity is a fundamental feature of neocortical circuits. The aim of this project is unravel homeostatic mechanisms that ensure functional stability of neuronal ensembles forming auditory representations in a dynamic cortical architecture. To that goal, we combine in vivo two-photon imaging approaches in mice with theoretical modelling with our collaboration partner Prof. Yonatan Loewenstein at the Hebrew University in Jerusalem, to elucidate the link between volatility at the connectivity level and functionality at the level of neuronal ensembles.» weiterlesen» einklappen

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