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Histological and histomorphometric investigation of the median palatine suture in different age groups - an ex vivo study on human cadaver specimens

Laufzeit: 01.01.2017 - 31.12.2022

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Kurzfassung


The median palatine suture of the maxilla, which extends from the maxillary incisal fossa to the nasal posterior spine, is of great clinical importance and relevance to orthodontists worldwide. A rapid maxillary expansion (RME) is indicated in the presence of a a narrow upper jaw and / or a one- or bilateral crossbite and / or frontal crowding in order to create space as fast as possible in the transversal.
As the patient ages, the so-called transversal resistance of the median palatine suture...
The median palatine suture of the maxilla, which extends from the maxillary incisal fossa to the nasal posterior spine, is of great clinical importance and relevance to orthodontists worldwide. A rapid maxillary expansion (RME) is indicated in the presence of a a narrow upper jaw and / or a one- or bilateral crossbite and / or frontal crowding in order to create space as fast as possible in the transversal.
As the patient ages, the so-called transversal resistance of the median palatine suture becomes larger and thus, it becomes increasingly difficult to predict the success of a conservative RME. Therefore, in patients > 18 years, surgically assisted RME is usually preferred to conservative RME.
Assumptions that the increasing ossification of the suture are responsible for this resistance can only be partially verified. Previous studies showed that at the age of 30 years, only a very small portion of the median suture is clearly ossified, which means that there is still a need for considerable examinations / ex vivo studies.
The aim of this study is to use modern histological and histomorphometric methods to analyze the age-related morphological changes of the median palatine suture in cooperation with Prof. Dr. Dr. Dr. Shahram Ghanaati, Senior Consultant and Head of the Research Laboratory (FORM-Lab, Frankfurt Orofacial Regenerative Medicine-Lab), the Department of Oral and Maxillofacial Surgery of the Goethe-University Frankfurt am Main (Director: Univ.-Prof. Dr. Dr. Robert Sader). Further insights into the transversal resistance of the median palatine sutura should be gained. The working hypothesis says that the age-dependent form changes of the suture, the horizontal and transversal interdigitations (twisting or toothing of the bone suture), respectively, could be responsible for this resistance.
 
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