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Neurobehavioral mechanisms of stress inoculation - a translational approach

Laufzeit: 01.01.2017 - 31.12.2020

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Kurzfassung


One of the most challenging endeavors in resilience research is to identify the neurobiological mechanisms that actively promote resilience. Experimentally, this can be achieved by investigating the molecular pathways that are either regulated following application of a pharmacological stimulus known to promote resilience (e.g. model compound ketamine) or via repeated exposures to a moderate, controllable stressor (i.e. the use of behavioral stress inoculation models). This translational...One of the most challenging endeavors in resilience research is to identify the neurobiological mechanisms that actively promote resilience. Experimentally, this can be achieved by investigating the molecular pathways that are either regulated following application of a pharmacological stimulus known to promote resilience (e.g. model compound ketamine) or via repeated exposures to a moderate, controllable stressor (i.e. the use of behavioral stress inoculation models). This translational study integrates data from stress inoculation models involving zebrafish, mouse and human.» weiterlesen» einklappen

Beteiligte Einrichtungen