Kurzfassung

A phase 3, multicenter, double-blind, randomized, placebo-controlled study of AG-120 or AG-221 in combination with induction therapy and consolidation therapy followed by maintenance therapy in patients with newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with excess blasts-2, with an IDH1 or IDH2 mutation, eligible for intensive chemotherapy or myelodysplastic syndromes with excess blasts-2 (MDS-EB2)