Kurzfassung

The aim of the project is to develop and bring to clinic new tools to stratify patients with autoimmune diseases (AID) in order to improve diagnosis, prognosis and personalize the treatment. To achieve this ambitious goal we designed a structured research program constituted of three complementary parts: 1. Selection of informative patients from our databases and generation of high throughput data for patient’s stratification 2. Explore new biomarkers, diagnostic tools and therapeutic targets...The aim of the project is to develop and bring to clinic new tools to stratify patients with autoimmune diseases (AID) in order to improve diagnosis, prognosis and personalize the treatment. To achieve this ambitious goal we designed a structured research program constituted of three complementary parts: 1. Selection of informative patients from our databases and generation of high throughput data for patient’s stratification 2. Explore new biomarkers, diagnostic tools and therapeutic targets by the study of tolerance checkpoints and phenotypic characteristics of autoimmune B cells 3. Design a clinical decision support tool by integration and analysis of acquired data. PERSONALIS is a French-German-Swiss cross-border cooperative project.» weiterlesen» einklappen