Inhaltszusammenfassung

The subject of this study is to model the physiologically realistic volumetric compliance of a humanoid carotid artery within a fluid-structure-interaction (FSI) simulation. CTA scans of a patient’s carotid artery are used to create a virtual twin geometry of a computational domain for fluid volume and vascular tissue. In vitro silicon replicas are used to validate the stress-strain relationship of the material used and to validate the simulation with laboratory compliance tests. Subsequ...The subject of this study is to model the physiologically realistic volumetric compliance of a humanoid carotid artery within a fluid-structure-interaction (FSI) simulation. CTA scans of a patient’s carotid artery are used to create a virtual twin geometry of a computational domain for fluid volume and vascular tissue. In vitro silicon replicas are used to validate the stress-strain relationship of the material used and to validate the simulation with laboratory compliance tests. Subsequently, a strain-dependent Young’s modulus is embedded in a highfidelity vessel simulation to adapt the linear elasticity model to the measured vessel inflation. Resistance outlet boundary conditions are derived in the FSI context and are applied to model the physiological flow and pressure waves. As a result of this study, the natural reservoir mechanic of arteries during systole, the Windkessel effect, is observed.» weiterlesen» einklappen

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Klassifikation

DFG Fachgebiet:
Mathematik

DDC Sachgruppe:
Mathematik