Starten Sie Ihre Suche...


Durch die Nutzung unserer Webseite erklären Sie sich damit einverstanden, dass wir Cookies verwenden. Weitere Informationen

Biofilm characterization from people with different mechanical Plaque removal profile

Laufzeit: 01.01.2015 - 31.12.2019

imported

Kurzfassung


This was a single-center, double-blind, 2-week, 1-treatment, parallel group study design. Thirty-nine (39) adult subjects, who showed evidence of dental plaque and who were routine manual toothbrush users were enrolled in this study and scheduled for a professional brushing visit. Subjects were instructed to refrain from all oral hygiene procedures for approximately 24 hours prior to their appointments. Of the initial 39, 20 subjects with repeatable plaque levels (at visits 1 and 2) were...This was a single-center, double-blind, 2-week, 1-treatment, parallel group study design. Thirty-nine (39) adult subjects, who showed evidence of dental plaque and who were routine manual toothbrush users were enrolled in this study and scheduled for a professional brushing visit. Subjects were instructed to refrain from all oral hygiene procedures for approximately 24 hours prior to their appointments. Of the initial 39, 20 subjects with repeatable plaque levels (at visits 1 and 2) were categorized to have either “hard-to-remove” or “easy-to-remove” plaque (10 subjects each) based on their professional-brushing plaque removal values and were selected for 3 more visits.On-site toothbrushing between pre- and post-brushing plaque assessments were standardized and performed by a dentist. Plaque was measured using DPIA (Digital Plaque Imaging Analysis). At visits 3 to 5 clinical specimens (supragingival plaque samples) were collected from the 20 selected subjects and stored following established techniques for subsequent analysis outside the study protocol. The plaque samples were analyzed for bio-mechanical, compositional and structural properties. At visit 3 subjects received a dental prophylaxis. Approximately 2 weeks later, subjects were invited to measure plaque levels using DPIA. Then they received a professional brushing after which post-brushing DPIA images were taken. Dental plaque was resampled and analyzed for endpoints mentioned above. Subjects then received treatment products (regular manual toothbrush and antibacterial fluoride toothpaste) to use at home for the next 2 weeks. At subject’s final visit (visit-5), the same assessments were conducted as for visit 4.Subjects completed a pre and post-treatment questionnaire about their nutrition behavior.» weiterlesen» einklappen

Beteiligte Einrichtungen