Prevalence of age-related macular degeneration in a large European cohort : results from the population-based Gutenberg Health Study
Graefe's archive for clinical and experimental ophthalmology. Bd. 252. H. 9. Berlin: Springer 2014 S. 1403 - 1411
Erscheinungsjahr: 2014
ISBN/ISSN: 0721-832x ; 1435-702X
Publikationstyp: Zeitschriftenaufsatz
Sprache: Englisch
Doi/URN: 10.1007/s00417-014-2591-9
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Inhaltszusammenfassung
BACKGROUND: The aim of this study was to describe the sex prevalence of age-related macular degeneration (AMD) and its correlation with urban or rural residence in a large and relatively young European cohort. METHODS: We evaluated fundus photographs from participants in the Gutenberg Health Study (GHS), a population-based, prospective, observational, single-centre study in the Rhineland-Palatine region in midwestern Germany. The participants were 35-74 years of age at enrolment. The fundus i...BACKGROUND: The aim of this study was to describe the sex prevalence of age-related macular degeneration (AMD) and its correlation with urban or rural residence in a large and relatively young European cohort. METHODS: We evaluated fundus photographs from participants in the Gutenberg Health Study (GHS), a population-based, prospective, observational, single-centre study in the Rhineland-Palatine region in midwestern Germany. The participants were 35-74 years of age at enrolment. The fundus images were classified as described in the Rotterdam Study and were graded independently by two experienced ophthalmologists (CK and UBK) based on the presence of hard and soft drusen, retinal pigmentary abnormalities, and signs of atrophic or neovascular age-related macular generation (AMD). RESULTS: Photographs from 4,340 participants were available for grading. Small, hard drusen (» weiterlesen» einklappen
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