A multi-cohort consortium for GEnder-Sensitive Analyses of mental health trajectories and implications for prevention (GESA) in the general population in Germany
BMJ OPEN. Bd. 10. H. 2. London: BMJ Publ. 2020 S. 1 - 10
Erscheinungsjahr: 2020
ISBN/ISSN: 2044-6055
Publikationstyp: Zeitschriftenaufsatz
Sprache: Englisch
Doi/URN: 10.1136/bmjopen-2019-034220
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Inhaltszusammenfassung
Introduction: Mental health is marked by gender differences. We formed a multi-cohort consortium to perform GEnder-Sensitive Analyses of mental health trajectories and study their implications for prevention (GESA). GESA aims at (1) identifying gender differences regarding symptoms and trajectories of mental health over the lifespan; (2) determining gender differences regarding the prevalence, impact of risk and protective factors; and (3) determining effects of mental health on primary a... Introduction: Mental health is marked by gender differences. We formed a multi-cohort consortium to perform GEnder-Sensitive Analyses of mental health trajectories and study their implications for prevention (GESA). GESA aims at (1) identifying gender differences regarding symptoms and trajectories of mental health over the lifespan; (2) determining gender differences regarding the prevalence, impact of risk and protective factors; and (3) determining effects of mental health on primary and secondary outcomes (eg, quality of life, healthcare behaviour and utilisation). Methods and analysis: We plan to perform secondary analyses on three major, ongoing, population-based, longitudinal cohorts (Gutenberg Health-Study (GHS), Study of Health in Pomerania (SHIP), Cooperative Health Research in the Augsburg Region (KORA)) with data on mental and somatic symptoms, medical assessments and diagnoses in north-east, middle and southern Germany (n>40 000). Meta-analytic techniques (using DataSHIELD framework) will be used to combine aggregated data from these cohorts. This process will inform about heterogeneity of effects. Longitudinal regression models will estimate sex-specific trajectories and effects of risk and protective factors and secondary outcomes. Ethics and dissemination: The cohorts were approved by the ethics committees of the Statutory Physician Board of Rhineland-Palatinate (837.020.07; GHS), the University of Greifswald (BB 39/08; SHIP) and the Bavarian Chamber of Physicians (06068; KORA). Together with stakeholders in medical care and medical training, findings will be translated and disseminated into gender-sensitive health promotion and prevention. » weiterlesen» einklappen
Autoren
Klassifikation
DFG Fachgebiet:
Medizin
DDC Sachgruppe:
Medizin