Kurzfassung

The SPECIAL project aims at delivering breakthrough technologies for the biotechnological production of cellular metabolites and extracellular biomaterials from marine sponges. These include a platform technology to produce secondary metabolites from a wide range of sponge species, a novel in vitro method for the production of biosilica and recombinant technology for the production of marine collagen. Research on cellular metabolites will be based upon our recent finding that non-growing...The SPECIAL project aims at delivering breakthrough technologies for the biotechnological production of cellular metabolites and extracellular biomaterials from marine sponges. These include a platform technology to produce secondary metabolites from a wide range of sponge species, a novel in vitro method for the production of biosilica and recombinant technology for the production of marine collagen. Research on cellular metabolites will be based upon our recent finding that non-growing sponges continuously release large amounts of cellular material. Production of biosilica will be realized through biosintering, a novel enzymatic process that was recently discovered in siliceous sponges. Research on sponge collagen will focus on finding the optimal conditions for expression of the related genes. Alongside this research, the project will identify and develop new products from sponges, thus fully realizing the promises of marine biotechnology. Specifically, the project will focus on potential anticancer drugs and novel biomedical/industrial applications of biosilica and collagen, hereby taking advantage of the unique physico-chemical properties of these extracellular sponge products. The consortium unites seven research institutions covering a wide range of marine biotechnology-related disciplines and four knowledge-intensive SMEs that are active in the field of sponge culture, drug development and nanobiotechnology.» weiterlesen» einklappen